Description:
MYK-461 is a myosin inhibitor that selectively decreases the ATPase activity of cardiac myosin heavy chain, thus it is potentially for the treatment of hypertrophic cardiomyopathy (HCM).
- Molecular Weight: 273.33
- Molecular Formula: C15H19N3O2
Purity: 99%
Canonical SMILES:
CC(C)N1C(=O)C=C(NC1=O)NC(C)C2=CC=CC=C2
InChI:
InChI=1S/C15H19N3O2/c1-10(2)18-14(19)9-13(17-15(18)20)16-11(3)12-7-5-4-6-8-12/h4-11,16H,1-3H3,(H,17,20)/t11-/m0/s1
InChIKey: RLCLASQCAPXVLM-NSHDSACASA-N
- Application: potential treatment of hypertrophic cardiomyopathy (HCM)
Synonyms:
SAR-439152; SAR 439152; SAR439152; MYK-461; MYK 461; MYK461; Mavacamten; 6-[[(1S)-1-phenylethyl]amino]-3-propan-2-yl-1H-pyrimidine-2,4-dione
More details are to be found on supplier website
