Description:
NCGC00244536 is a potent KDM4A inhibitor (IC50 = 10 nM) that inhibits the in vivo growth of tumors derived from PC3 cells and ex vivo human PCa explants.
- Molecular Weight: 382.45
- Molecular Formula: C25H22N2O2
Canonical SMILES:
C1=CC=C(C=C1)CCCNC(=O)C2=CC=CC(=C2)C3=CC(=C4C(=C3)C=CC=N4)O
InChI:
1S/C25H22N2O2/c28-23-17-22(16-20-12-6-13-26-24(20)23)19-10-4-11-21(15-19)25(29)27-14-5-9-18-7-2-1-3-8-18/h1-4,6-8,10-13,15-17,28H,5,9,14H2,(H,27,29)
InChIKey: NYKBXXGHEMXSBB-UHFFFAOYSA-N- Boiling Point: 646.9±55.0 °C at 760 Torr
- Solubility: DMSO: ≥ 100 mg/mL
- Storage: Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms:
KDM4B-IN-B3; KDM4B IN B3; KDM4BINB3; 3-(8-hydroxyquinolin-6-yl)-N-(3-phenylpropyl)benzamide; CHEMBL3785491; BDBM50158844
More details are to be found on supplier website
