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ONO-4059 (hydrochloride)
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ONO-4059 (hydrochloride)
BGC Id:
161217888207
CAS No:
1439901-97-9
Synonyms:
Molecular Formula:
Molecular Weight:
EINECS:
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Description
: ONO-4059 (hydrochloride) is the hydrochloride salt form of Tirabrutinib. ONO-4059 is a highly selective, orally bioavailable BTK inhibitor (IC50= 2.2 nM) and demonstrated therapeutic efficacy in a mouse arthritis model.
Molecular Weight
: 490.95
Molecular Formula
: C25H23ClN6O3
Canonical SMILES
:
O=C(N1C[C@@H](CC1)N(C2=O)C3=NC=NC(N)=C3N2C4=CC=C(C=C4)OC5=CC=CC=C5)C#CC.[H]Cl
InChI
:
ONO-4059 HCl
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