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Suppliers for
Seneciphyllin
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Properties | CAS |
480-81-9 | Formula |
C18H23NO5 |
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6 Registered suppliers
Molecular Formula: C18H23NO5 Molecular Weight: 333.38 Hazard Symbols: T UN Number: 1544 WGKGermany: 3 PackingGroup: III
Description : Seneciphylline, a natural pyrrolizidine alkaloid isolated from the herbs of Senecio scandens, may cause reduction of cytochrome P-450 and related monooxygenase activities. Seneciphylline is a pyrrolizidine alkaloid with the potential to affect hepatic drug metabolizing enzymes in rat cells. In vitro, seneciphylline has no effection on hepatic drug metabolizing enzymes, but has seneciphyllineslight activity of reducing aminopyrine demethylase. - Molecular Weight :333.4
- Boiling Point :470.34°C (rough estimate)
- Melting Point :217°C
- Purity :> 98%
Molecular Formula : C18H23NO5 Canonical SMILES : CC=C1CC(=C)C(C(=O)OCC2=CCN3C2C(CC3)OC1=O)(C)O InChI : InChI=1S/C18H23NO5/c1-4-12-9-11(2)18(3,22)17(21)23-10-13-5-7-19-8-6-14(15(13)19)24-16(12)20/h4-5,14-15,22H,2,6-10H2,1,3H3/b12-4-/t14-,15-,18-/m1/s1 InChIKey : FCEVNJIUIMLVML-QPSVUOIXSA-N Solubility : less than 0.1 mg/mL at 64 °F Appearance : Powder Storage : -20°C Synonyms : Jacodine; (15cis)-12-Hydroxy-13,19-didehydrosenecionan-11,16-dione; 13,19-didehydro-12-hydroxysenecionan-11,16-dione
More details are to be found here
Description : Seneciphylline, a natural pyrrolizidine alkaloid isolated from the herbs of Senecio scandens, may cause reduction of cytochrome P-450 and related monooxygenase activities. Seneciphylline is a pyrrolizidine alkaloid with the potential to affect hepatic drug metabolizing enzymes in rat cells. In vitro, seneciphylline has no effection on hepatic drug metabolizing enzymes, but has seneciphyllineslight activity of reducing aminopyrine demethylase. - Molecular Weight :333.4
- Boiling Point :470.34°C (rough estimate)
- Melting Point :217°C
- Purity :> 98%
Molecular Formula : C18H23NO5 Canonical SMILES : CC=C1CC(=C)C(C(=O)OCC2=CCN3C2C(CC3)OC1=O)(C)O InChI : InChI=1S/C18H23NO5/c1-4-12-9-11(2)18(3,22)17(21)23-10-13-5-7-19-8-6-14(15(13)19)24-16(12)20/h4-5,14-15,22H,2,6-10H2,1,3H3/b12-4-/t14-,15-,18-/m1/s1 InChIKey : FCEVNJIUIMLVML-QPSVUOIXSA-N Solubility : less than 0.1 mg/mL at 64 °F Appearance : Powder Storage : -20°C Synonyms : Jacodine; (15cis)-12-Hydroxy-13,19-didehydrosenecionan-11,16-dione; 13,19-didehydro-12-hydroxysenecionan-11,16-dione
More details are to be found here
Description : Seneciphylline, a natural pyrrolizidine alkaloid isolated from the herbs of Senecio scandens, may cause reduction of cytochrome P-450 and related monooxygenase activities. Seneciphylline is a pyrrolizidine alkaloid with the potential to affect hepatic drug metabolizing enzymes in rat cells. In vitro, seneciphylline has no effection on hepatic drug metabolizing enzymes, but has seneciphyllineslight activity of reducing aminopyrine demethylase. - Molecular Weight :333.4
- Boiling Point :470.34°C (rough estimate)
- Melting Point :217°C
- Purity :> 98%
Molecular Formula : C18H23NO5 Canonical SMILES : CC=C1CC(=C)C(C(=O)OCC2=CCN3C2C(CC3)OC1=O)(C)O InChI : InChI=1S/C18H23NO5/c1-4-12-9-11(2)18(3,22)17(21)23-10-13-5-7-19-8-6-14(15(13)19)24-16(12)20/h4-5,14-15,22H,2,6-10H2,1,3H3/b12-4-/t14-,15-,18-/m1/s1 InChIKey : FCEVNJIUIMLVML-QPSVUOIXSA-N Solubility : less than 0.1 mg/mL at 64 °F Appearance : Powder Storage : -20°C Synonyms : Jacodine; (15cis)-12-Hydroxy-13,19-didehydrosenecionan-11,16-dione; 13,19-didehydro-12-hydroxysenecionan-11,16-dione
More details are to be found here
Description : Seneciphylline, a natural pyrrolizidine alkaloid isolated from the herbs of Senecio scandens, may cause reduction of cytochrome P-450 and related monooxygenase activities. Seneciphylline is a pyrrolizidine alkaloid with the potential to affect hepatic drug metabolizing enzymes in rat cells. In vitro, seneciphylline has no effection on hepatic drug metabolizing enzymes, but has seneciphyllineslight activity of reducing aminopyrine demethylase. - Molecular Weight :333.4
- Boiling Point :470.34°C (rough estimate)
- Melting Point :217°C
- Purity :> 98%
Molecular Formula : C18H23NO5 Canonical SMILES : CC=C1CC(=C)C(C(=O)OCC2=CCN3C2C(CC3)OC1=O)(C)O InChI : InChI=1S/C18H23NO5/c1-4-12-9-11(2)18(3,22)17(21)23-10-13-5-7-19-8-6-14(15(13)19)24-16(12)20/h4-5,14-15,22H,2,6-10H2,1,3H3/b12-4-/t14-,15-,18-/m1/s1 InChIKey : FCEVNJIUIMLVML-QPSVUOIXSA-N Solubility : less than 0.1 mg/mL at 64 °F Appearance : Powder Storage : -20°C Synonyms : Jacodine; (15cis)-12-Hydroxy-13,19-didehydrosenecionan-11,16-dione; 13,19-didehydro-12-hydroxysenecionan-11,16-dione
More details are to be found here
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Properties:
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Last update 2024-06-12
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