Product Name: (+)-Camptothecin
CAS: 7689-03-4
MF: C20H16N2O4
MW: 348.35
EINECS: 444-280-6
Mp: 260 °C (Dec.)(Lit.)
Storage Temp.: 2-8°C
Solubility: Chloroform/Methanol (4:1): 4 Mg/Ml
Form: Solid
Color: Yellow
Water Solubility: Insoluble
Merck: 1735
Chemical Properties light yellow crystal powde
Usage :antineoplastic
Usage : Antitumor agent;Topoisomerase I inhibitor
Usage: 10-hydroxycamptothecine precursor, topoisomerase inhibitor, binds irreversibly to DNA-topoisomerase I complex
Usage :Antitumor alkaloid. Binds irreversible to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. A cytotoxic antitumor agent
Biological Activity: Cytotoxic plant alkaloid with antitumor properties; prototypic DNA topoisomerase I inhibitor.