BGC > Product Search > Jatrorrhizine hydrochloride | 6681-15-8

Molecular Formula: C20H20NO4.ClH
Molecular Weight: 374.842
HS Code: 29399990

Molecular Formula: C20H21ClNO4+
Molecular Weight: 374.84

Description :
Jatrorrhizine Hydrochloride (JH), an active component of the traditional Chinese medicinal herb Coptis chinensis, inhibited the proliferation and neovascularization of C8161 human metastatic melanoma cells. The effective inhibitory effects of Jatrorrhizine Hydrochloride on metastatic melanoma cell proliferation and neovascularization with low toxicity suggest that Jatrorrhizine Hydrochloride is a potential new antimelanoma drug candidate.

• Molecular Weight :373.83
• Melting Point :208-210°C
• Purity :> 98%

Molecular Formula :
C20H20ClNO4
Canonical SMILES :
COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)O)OC)OC.[Cl-]
InChI :
InChI=1S/C20H19NO4.ClH/c1-23-18-5-4-12-8-16-14-10-19(24-2)17(22)9-13(14)6-7-21(16)11-15(12)20(18)25-3;/h4-5,8-11H,6-7H2,1-3H3;1H
InChIKey :
JKMUUZMCSNHBAX-UHFFFAOYSA-N
Solubility :
Soluble in Methanol (Slightly, Heated)
Appearance :
Orange Solid
Storage : Store at -20°C under inert atmosphere
Synonyms :
Dibenzo[a,g]quinolizinium, 5,6-dihydro-3-hydroxy-2,9,10-trimethoxy-, chloride (1:1); Berbinium, 7,8,13,13a-tetradehydro-3-hydroxy-2,9,10-trimethoxy-, chloride; Dibenzo[a,g]quinolizinium, 5,6-dihydro-3-hydroxy-2,9,10-trimethoxy-, monochloride; Jatrorrhizine chloride; Neprotine chloride; NSC 645313

More details are to be found here

Description :
Jatrorrhizine Hydrochloride (JH), an active component of the traditional Chinese medicinal herb Coptis chinensis, inhibited the proliferation and neovascularization of C8161 human metastatic melanoma cells. The effective inhibitory effects of Jatrorrhizine Hydrochloride on metastatic melanoma cell proliferation and neovascularization with low toxicity suggest that Jatrorrhizine Hydrochloride is a potential new antimelanoma drug candidate.

• Molecular Weight :373.83
• Melting Point :208-210°C
• Purity :> 98%

Molecular Formula :
C20H20ClNO4
Canonical SMILES :
COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)O)OC)OC.[Cl-]
InChI :
InChI=1S/C20H19NO4.ClH/c1-23-18-5-4-12-8-16-14-10-19(24-2)17(22)9-13(14)6-7-21(16)11-15(12)20(18)25-3;/h4-5,8-11H,6-7H2,1-3H3;1H
InChIKey :
JKMUUZMCSNHBAX-UHFFFAOYSA-N
Solubility :
Soluble in Methanol (Slightly, Heated)
Appearance :
Orange Solid
Storage : Store at -20°C under inert atmosphere
Synonyms :
Dibenzo[a,g]quinolizinium, 5,6-dihydro-3-hydroxy-2,9,10-trimethoxy-, chloride (1:1); Berbinium, 7,8,13,13a-tetradehydro-3-hydroxy-2,9,10-trimethoxy-, chloride; Dibenzo[a,g]quinolizinium, 5,6-dihydro-3-hydroxy-2,9,10-trimethoxy-, monochloride; Jatrorrhizine chloride; Neprotine chloride; NSC 645313

More details are to be found here