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Suppliers for
Ly-900009
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Properties | CAS |
209984-68-9 |
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1 Registered suppliers
Description : LY-900009 is a small-molecule inhibitor of Notch signalling with IC50 value of 0.27 nM via selective inhibition of the γ-secretase protein. LY-900009 was developed as a candidate therapeutic drug against AD (IDENTITY trial), which failed in phase III trials. - Molecular Weight :409.486
- Purity :> 98%
Molecular Formula : C23H27N3O4 Canonical SMILES : CC(C)C(C(=O)NC(C)C(=O)NC1C2=CC=CC=C2C3=CC=CC=C3N(C1=O)C)O InChI : InChI=1S/C23H27N3O4/c1-13(2)20(27)22(29)24-14(3)21(28)25-19-17-11-6-5-9-15(17)16-10-7-8-12-18(16)26(4)23(19)30/h5-14,19-20,27H,1-4H3,(H,24,29)(H,25,28)/t14-,19-,20-/m0/s1 InChIKey : JURYTIUJMYPBNN-GKCIPKSASA-N Appearance : Off-white Solid Application : Gamma Secretase Inhibitors and Modulators Synonyms : LY900009; LY-900009; LY 900009; (2S)-2-hydroxy-3-methyl-N-[(2S)-1-[[(7S)-5-methyl-6-oxo-7H-benzo[d][1]benzazepin-7-yl]amino]-1-oxopropan-2-yl]butanamide
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Ly-900009
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Last update 2024-06-12
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