BGC > Product Search > Sb 239063 | 193551-21-2

Molecular Formula: C20H21FN4O2
Molecular Weight: 368.4
WGKGermany: 3

Molecular Formula: C20H21FN4O2
Molecular Weight: 368.4
WGKGermany: 3

Description :
SB239063 is a potent p38MAPK inhibitor. SB 239063 had an IC(50) of 44 nM for inhibition of recombinant purified human p38alpha. In lipopolysaccharide-stimulated human peripheral blood monocytes, SB 239063 inhibited interleukin-1 and tumor necrosis factor-alpha production. SB 239063 may be useful for the treatment of asthma and other inflammatory disorders.

• Molecular Weight :368.412
• Purity :0.98

Molecular Formula :
C20H21FN4O2
Canonical SMILES :
COC1=NC=CC(=N1)C2=C(N=CN2C3CCC(CC3)O)C4=CC=C(C=C4)F
InChI :
InChI=1S/C20H21FN4O2/c1-27-20-22-11-10-17(24-20)19-18(13-2-4-14(21)5-3-13)23-12-25(19)15-6-8-16(26)9-7-15/h2-5,10-12,15-16,26H,6-9H2,1H3
InChIKey :
ZQUSFAUAYSEREK-UHFFFAOYSA-N
Appearance :
White to off-white solid
Application :
Protein Kinase Inhibitors
Synonyms :
SB-239063; SB 239063.

More details are to be found here