BGC > Product Search > Escitalopram | 128196-01-0

Molecular Formula: C20H21FN2O
Molecular Weight: 324,39

Molecular Formula: C20H21FN2O
Molecular Weight: 324,39

Description :
Escitalopram, the S-enantiomer of citalopram, belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). Escitalopram may be used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD). Escitalopram has no significant affinity for adrenergic (alpha1, alpha2, beta), cholinergic, GABA, dopaminergic, histaminergic, serotonergic (5HT1A, 5HT1B, 5HT2), or benzodiazepine receptors; antagonism of such receptors has been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs. The chronic administration of escitalopram is found to downregulate brain norepinephrine receptors, as has been observed with other drugs effective in the treatment of major depressive disorder. Escitalopram does not inhibit monoamine oxidase.

• Molecular Weight :324.39
• Melting Point :147-152C
• Purity :> 98%

Molecular Formula :
C20H21FN2O
Canonical SMILES :
CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F
InChI :
InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3/t20-/m0/s1
InChIKey :
WSEQXVZVJXJVFP-FQEVSTJZSA-N
Solubility :
Sparingly soluble
Application :
Serotonin uptake inhibitors; antidepressive agents, Second-generation
Synonyms :
(S)-Citalopram; S-(+)-Citalopram; Seroplex

More details are to be found here

Description :
Escitalopram, the S-enantiomer of citalopram, belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). Escitalopram may be used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD). Escitalopram has no significant affinity for adrenergic (alpha1, alpha2, beta), cholinergic, GABA, dopaminergic, histaminergic, serotonergic (5HT1A, 5HT1B, 5HT2), or benzodiazepine receptors; antagonism of such receptors has been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs. The chronic administration of escitalopram is found to downregulate brain norepinephrine receptors, as has been observed with other drugs effective in the treatment of major depressive disorder. Escitalopram does not inhibit monoamine oxidase.

• Molecular Weight :324.39
• Melting Point :147-152C
• Purity :> 98%

Molecular Formula :
C20H21FN2O
Canonical SMILES :
CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F
InChI :
InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3/t20-/m0/s1
InChIKey :
WSEQXVZVJXJVFP-FQEVSTJZSA-N
Solubility :
Sparingly soluble
Application :
Serotonin uptake inhibitors; antidepressive agents, Second-generation
Synonyms :
(S)-Citalopram; S-(+)-Citalopram; Seroplex

More details are to be found here