BGC > Product Search > Coluracetam

Molecular Formula: C19H23N3O3
Molecular Weight: 341.4

Molecular Formula: C19H23N3O3
Molecular Weight: 341.4

EINECS :1308068-626-2
Molecular formula :C19H23N3O3

EINECS :1308068-626-2
Molecular formula :C19H23N3O3

EINECS :1308068-626-2
Molecular formula :C19H23N3O3

EINECS :1308068-626-2
Molecular formula :C19H23N3O3

EINECS :1308068-626-2
Molecular formula :C19H23N3O3

EINECS :1308068-626-2
Molecular formula :C19H23N3O3

Description :
MKC-231 (10(-10)-10(-6) moll) significantly increased high affinity choline uptake (HACU) when it was incubated with the hippocampal synaptosomes of ethylcholine mustard aziridinium ion (AF64A) treated rats, but not of normal rats. MKC-231 did not affect the AChE activity, [3H]- quinuclidinyl benzilate binding, and [3H]-pirenzepine binding. Oral administration of MKC-231 (1-10 mg/kg) significantly improved the learning deficits in the Morris' water maze of AF64A-treated rats, but it did not produce any significant side effects, like tremor, salivation or hypothermia, which were observed in rats treated with high doses of tacrine [1]. In acute behavioral experiments, MKC-231 and THA had no significant effect on AF64A-induced memory deficits at any doses tested (0.3, 1.0 and 3.0 mg/kg), whereas Dup 996, at a dose of 1.0 mg/kg, significantly improved memory deficits. In chronic experiments, MKC-231 improved memory deficit at all doses tested (0.3, 1.0, or 3.0 mg/kg p.o., once daily for 11 days) and Dup 996 did so only at a dose of 3.0 mg/kg, whereas THA did not improve memory deficit at any doses tested.

• Molecular Weight :341.4
• Purity :> 98%

Molecular Formula :
C19H23N3O3
Canonical SMILES :
CC1=C(OC2=NC3=C(CCCC3)C(=C12)NC(=O)CN4CCCC4=O)C
InChI :
InChI=1S/C19H23N3O3/c1-11-12(2)25-19-17(11)18(13-6-3-4-7-14(13)20-19)21-15(23)10-22-9-5-8-16(22)24/h3-10H2,1-2H3,(H,20,21,23)
InChIKey :
PSPGQHXMUKWNDI-UHFFFAOYSA-N
Synonyms :
Coluracetam; BCI-540; MKC-231; BCI 540; MKC 231; BCI540; MKC231.

More details are to be found here

Description :
MKC-231 (10(-10)-10(-6) moll) significantly increased high affinity choline uptake (HACU) when it was incubated with the hippocampal synaptosomes of ethylcholine mustard aziridinium ion (AF64A) treated rats, but not of normal rats. MKC-231 did not affect the AChE activity, [3H]- quinuclidinyl benzilate binding, and [3H]-pirenzepine binding. Oral administration of MKC-231 (1-10 mg/kg) significantly improved the learning deficits in the Morris' water maze of AF64A-treated rats, but it did not produce any significant side effects, like tremor, salivation or hypothermia, which were observed in rats treated with high doses of tacrine [1]. In acute behavioral experiments, MKC-231 and THA had no significant effect on AF64A-induced memory deficits at any doses tested (0.3, 1.0 and 3.0 mg/kg), whereas Dup 996, at a dose of 1.0 mg/kg, significantly improved memory deficits. In chronic experiments, MKC-231 improved memory deficit at all doses tested (0.3, 1.0, or 3.0 mg/kg p.o., once daily for 11 days) and Dup 996 did so only at a dose of 3.0 mg/kg, whereas THA did not improve memory deficit at any doses tested.

• Molecular Weight :341.4
• Purity :> 98%

Molecular Formula :
C19H23N3O3
Canonical SMILES :
CC1=C(OC2=NC3=C(CCCC3)C(=C12)NC(=O)CN4CCCC4=O)C
InChI :
InChI=1S/C19H23N3O3/c1-11-12(2)25-19-17(11)18(13-6-3-4-7-14(13)20-19)21-15(23)10-22-9-5-8-16(22)24/h3-10H2,1-2H3,(H,20,21,23)
InChIKey :
PSPGQHXMUKWNDI-UHFFFAOYSA-N
Synonyms :
Coluracetam; BCI-540; MKC-231; BCI 540; MKC 231; BCI540; MKC231.

More details are to be found here

Purity : 98%
Smile code : O=C(NC1=C2C(OC(C)=C2C)=NC3=C1CCCC3)CN4C(CCC4)=O
MDL Number : MFCD00901416
MolFormula : C19H23N3O3
MolWeight : 341.4042
Available in stock : 22.358

Purity : 98%
Smile code : O=C(NC1=C2C(OC(C)=C2C)=NC3=C1CCCC3)CN4C(CCC4)=O
MDL Number : MFCD00901416
MolFormula : C19H23N3O3
MolWeight : 341.4042
Available in stock : 22.358

Purity : 98%
Smile code : O=C(NC1=C2C(OC(C)=C2C)=NC3=C1CCCC3)CN4C(CCC4)=O
MDL Number : MFCD00901416
MolFormula : C19H23N3O3
MolWeight : 341.4042
Available in stock : 22.358

Purity : 98%
Smile code : O=C(NC1=C2C(OC(C)=C2C)=NC3=C1CCCC3)CN4C(CCC4)=O
MDL Number : MFCD00901416
MolFormula : C19H23N3O3
MolWeight : 341.4042
Available in stock : 22.358