BGC > Produktsuche > Fedratinib | 936091-26-8

Molecular Formula: C27H36N6O3S
Molecular Weight: 524.68
HS Code: 29350090

Description:
Fedratinib is a potent and selective JAK2 inhibitor with IC50 value of 6 nM. It also exhibits inhibitory effects against FLT3 (IC50 = 25 nM), RET (IC50 = 17 nM) and JAK3 (IC50 = 169 nM).

• Molecular Weight:524.68
• Melting Point:180-182°C
• Purity:>98%

Molecular Formula:
C27H36N6O3S
Canonical SMILES:
CC1=CN=C(N=C1NC2=CC(=CC=C2)S(=O)(=O)NC(C)(C)C)NC3=CC=C(C=C3)OCCN4CCCC4
InChI:
InChI=1S/C27H36N6O3S/c1-20-19-28-26(30-21-10-12-23(13-11-21)36-17-16-33-14-5-6-15-33)31-25(20)29-22-8-7-9-24(18-22)37(34,35)32-27(2,3)4/h7-13,18-19,32H,5-6,14-17H2,1-4H3,(H2,28,29,30,31)
InChIKey:
JOOXLOJCABQBSG-UHFFFAOYSA-N
Solubility:
4µg/mL
Appearance:
White Solid
Synonyms:
TG101348; TG 101348; TG-101348; SAR302503; SAR-302503; SAR 302503; Fedratinib; N-tert-butyl-3-[[5-methyl-2-[4-(2-pyrrolidin-1-ylethoxy)anilino]pyrimidin-4-yl]amino]benzenesulfonamide

Purity: 98%
Smile code: O=S(C1=CC=CC(NC2=NC(NC3=CC=C(C=C3)OCCN4CCCC4)=NC=C2C)=C1)(NC(C)(C)C)=O
MDL Number: MFCD12922515
MolFormula: C27H36N6O3S
MolWeight: 524.6781
Available in stock: 12.672

Smile code:
O=S(C1=CC=CC(NC2=NC(NC3=CC=C(C=C3)OCCN4CCCC4)=NC=C2C)=C1)(NC(C)(C)C)=O
MDL Number:
MFCD12922515
Purity :
98%
Available in stock:
22.66 g